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Nat-20(S)-yne
Artikelnummer: Cay9001369-1
Smoothened (SMO) is a GPCR-like receptor which, with Patched, mediates hedgehog signaling to regulate gene expression through the Gli transcription factors. 20(S)-hydroxy Cholesterol (20(S)-OHC) is an oxysterol which binds SMO and activates hedgehog signaling (EC50 = 3 µM), and this activation is selective for the...
| Schlagworte: | Click Tag(TM) Nat-20(S)-yne, 26,27-dinorcholest-5-en-24-yne-3beta,20-diol |
| Anwendung: | Allosteric SMO activator |
| CAS | 1397692-46-4 |
| MW: | 370.6 D |
ab 82,00 €
