Zu "1396772-26-1" wurden 3 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
EPZ005687
Artikelnummer: TGM-T1905-100mg
Description: EPZ005687, a potent and selective inhibitor of EZH2. Target: Histone Methyltransferase. Smiles: Cc1cc(C)c(CNC(=O)c2cc(cc3n(ncc23)C2CCCC2)-c2ccc(CN3CCOCC3)cc2)c(=O)[nH]1. References: Knutson SK, et al. Nat Chem Biol, 2012, 8(11), 890-896.
| Anwendung: | Lysine methyltranferase EZH2 inhibitor |
| CAS | 1396772-26-1 |
| MW: | 539.67 D |
ab 53,00 €
EPZ005687
Artikelnummer: Cay13966-5
EPZ005687 is a potent, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 24 nM), the enzymatic subunit of polycomb repressive complex 2 (PRC2). It acts competitively with the EZH2 substrate S-adenosylmethionine. EPZ005687 has greater than 500-fold selectivity against 15 other protein methyltransferases...
| Schlagworte: | 1-cyclopentyl-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-6-[4-(4-morpholinylmethyl)phenyl]-1H-indazole-4-carbo... |
| Anwendung: | Lysine methyltranferase EZH2 inhibitor |
| CAS | 1396772-26-1 |
| MW: | 539.7 D |
ab 117,00 €
EPZ005687
Artikelnummer: LKT-E6396.1
A potent inhibitor of EZH2 (K(i) of 24 nM). EPZ005687 has greater than 500-fold selectivity against 15 other protein methyltransferases and has 50-fold selectivity against the closely related enzyme EZH1.
| Schlagworte: | EPZ-005687,... |
| Anwendung: | EZH2 inhibitor |
| CAS | 1396772-26-1 |
| MW: | 539.67 D |
ab 83,00 €
