Zu "138489-18-6" wurden 3 Artikel gefunden!
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Ro 31-8220 Mesylate
Artikelnummer: TGM-T6643-100mg
Description: Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor for PKC-alpha/betaI/betaII/gamma/epsilon (IC50: 5/24/14/27/24 nM), and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3beta. Target: PKC. Smiles:...
| Schlagworte: | Bisindolylmaleimide IX mesylate, Ro 31-8220 methanesulfonate, Bisindolylmaleimide IX |
| Anwendung: | PKC inhibitor |
| CAS | 138489-18-6 |
| MW: | 553.65 D |
ab 45,00 €
Bisindolylmaleimide IX (mesylate)
Artikelnummer: Cay13334-1
Bisindolylmaleimide IX (BIM IX) is a potent, cell-permeable inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively). It is a poor inhibitor of protein kinase A (PKA, IC50 = 0.9 µM) and calcium/calmodulin kinase II...
| Schlagworte: | BIM IX, Ro 31-8220, carbamimidothioic acid,... |
| Anwendung: | PKC inhibitor |
| CAS | 138489-18-6 |
| MW: | 553.7 D |
ab 61,00 €
Bisindolylmaleimide IX-Methansulfonate
Artikelnummer: AG-CR1-0111-M001
Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Transcription inhibitor. Induces TNF receptor family-mediated cell death. Pim-1 kinase...
| Schlagworte: | Ro 31-8220, BIM IX |
| Anwendung: | PKC inhibitor |
| CAS | 138489-18-6 |
ab 66,00 €
