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Lanabecestat
Artikelnummer: TGM-TQ0238-1mg
Description: Lanabecestat (AZD3293) is a highly potent and highly permeable, orally active BACE1 inhibitor (Ki: 0.4 nM) that crosses the blood-brain barrier, Lanabecestat can be used for the study of neurological diseases like Alzheimer's disease. Target: BACE. Smiles:...
| Schlagworte: | AZD3293, LY3314814 |
| Anwendung: | Targets beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46] (BACE1) |
| CAS | 1383982-64-6 |
| MW: | 412.53 D |
148,00 €
AZD 3293
Artikelnummer: Cay24934-1
AZD 3293 is an inhibitor of beta-secretase 1 (BACE1) and BACE2 (Kis = 0.4 and 0.8 nM, respectively). It is selective for BACE1 and BACE2 over cathepsin D, gamma-secretase, and human-ether-a-go-go (hERG, IC50s = 3,797, >25,000, and 4,700 nM, respectively). AZD 3293 inhibits the secretion of amyloid-beta (1-40)...
| Schlagworte: | Lanabecestat, LY3314814,... |
| Anwendung: | BACE1 / BACE2 inhibitor |
| CAS | 1383982-64-6 |
| MW: | 412.5 D |
ab 90,00 €
