Zu "1383716-40-2" wurden 2 Artikel gefunden!
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Vps34-PIK-III
Artikelnummer: TGM-T6945-100mg
Description: Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates. Target: PI3K, Autophagy. Smiles: Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1. References: Honda A, et al. Potent, Selective, and Orally Bioavailable...
| Schlagworte: | PIK-III, VPS34-IN2 |
| Anwendung: | VPS34 inhibitor |
| CAS | 1383716-40-2 |
| MW: | 319.36 D |
ab 49,00 €
PIK-III
Artikelnummer: Cay17002-1
PIK-III is an inhibitor of the type 3 phosphatidylinositol 3-kinase (PI3K) vacuolar protein sorting 34 (Vps34) that binds a unique hydrophobic pocket (IC50 = 18 nM). It is selective for Vps34 over related PI3K isoforms, PI4Kbeta, and mTOR. PIK-III acutely inhibits autophagy and de novo lipidation of LC3, leading to...
| Schlagworte: | Vacuolar Protein Sorting 34 Inhibitor 2, Vps34 Inhibitor 2, Vps34-IN2,... |
| Anwendung: | VPS34 inhibitor |
| CAS | 1383716-40-2 |
| MW: | 319.4 D |
ab 102,00 €
