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Agomelatine
Artikelnummer: TGM-T1445-100mg
Description: Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Target: 5-HT Receptor, Melatonin Receptor. Smiles: COC1=CC=C2C=CC=C(CCNC(C)=O)C2=C1....
| Schlagworte: | S-20098, Thymanax, Valdoxan |
| Anwendung: | Targets 5-hydroxytryptamine receptor 2 (HTR2) |
| CAS | 138112-76-2 |
| MW: | 243.3 D |
ab 56,00 €
Agomelatine
Artikelnummer: Cay13203-5
Agomelatine is an agonist of melatonin (MT) receptors and a derivative of melatonin (Cay-14427). It binds to MT1 and MT2 receptors (Kis = 0.14 and 0.41 nM, respectively) and has an EC50 value of 0.1 nM in a [35S]GTPgammaS binding assay using CHO cells expressing MT2 receptors. Agomelatine is also an antagonist of...
| Schlagworte: | S20098, N-[2-(7-methoxy-1-naphthalenyl)ethyl]-acetamide |
| Anwendung: | Melatonin analog |
| CAS | 138112-76-2 |
| MW: | 243.3 D |
ab 93,00 €
Agomelatine
Artikelnummer: LKT-A2658.50
Agomelatine is a melatonin receptors (MT1 and MT2) agonist and 5-HT2C antagonist.
| Anwendung: | 5-HT2C antagonist |
| CAS | 138112-76-2 |
| MW: | 243,3 D |
ab 133,00 €
