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ML198
Artikelnummer: TGM-T8986-100mg
Description: ML198 is a novel activator and non-inhibitory chaperone of glucocerebrosidase. ML198 serves as a starting point to develop a novel approach towards small molecule treatment for patients suffering from Gaucher disease. Target: Glucokinase. Smiles: Cc1cc(C)n2ncc(C(=O)Nc3ccc(cc3)C#C)c2n1. References:...
| Anwendung: | Glucocerebrosidase chemical chaperone |
| CAS | 1380716-06-2 |
| MW: | 290.32 D |
ab 40,00 €
ML-198
Artikelnummer: Cay37755-1
ML-198 is a chemical chaperone of glucocerebrosidase. It activates hydrolysis of the fluorescent glucocerebrosidase substrate 4-methylumbelliferyl-beta-D-glucopyranoside (4-MUG, Cay-20948) in spleen homogenate isolated from patients with Gaucher disease with the homozygous N370S mutant of glucocerebrosidase...
| Schlagworte: | NCGC758, N-(4-ethynylphenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidine-3-carboxamide |
| Anwendung: | Glucocerebrosidase chemical chaperone |
| CAS | 1380716-06-2 |
| MW: | 290.3 D |
ab 54,00 €
