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M2698
Artikelnummer: TGM-T11928-100mg
Description: M2698 (MSC2363318A) is an inhibitor of p70S6K, Akt1 and Akt3 with IC50s of 1 nM. M2698 shows anti-cancer activity. Target: mTOR, Akt. Smiles: N([C@H](CN1CCC1)C2=CC(C(F)(F)F)=C(Cl)C=C2)C=3C4=C(C(C(N)=O)=CC=C4)N=CN3. References: Machl A, et al. M2698 is a potent dual-inhibitor of p70S6K and Akt that...
| Schlagworte: | MSC2363318A |
| Anwendung: | P70S6K / Akt1 dual inhibitor |
| CAS | 1379545-95-5 |
| MW: | 449.86 D |
ab 43,00 €
M2698
Artikelnummer: LKT-M002698.1
Dual inhibitor of p70S6K and Akt.
| Schlagworte: | M 2698, M-2698, MSC-2363318A |
| Anwendung: | Dual p70S6K / Akt inhibitor |
| CAS | 1379545-95-5 |
| MW: | 449.86 D |
ab 161,00 €
M2698
Artikelnummer: Cay36816-1
M2698 is a dual inhibitor of p70 ribosomal S6 kinase (p70S6K) and Akt1 (IC50s = 1.1 and 4 nM, respectively). It is selective for p70S6K and Akt1 over Aurora B kinase (IC50 = 170 nM), as well as a panel of 265 kinases at 1 µM, but also inhibits protein kinase A (PKA), p90 ribosomal S6 kinase 1 (MSK1), MSK2,...
| Schlagworte: | MSC2363318A, 4-[[(1S)-2-(1-azetidinyl)-1-[4-chloro-3-(trifluoromethyl)phenyl]ethyl]amino]-8-quinazolinecarboxamide |
| Anwendung: | P70S6K / Akt1 dual inhibitor |
| CAS | 1379545-95-5 |
| MW: | 449.9 D |
ab 61,00 €
