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LDHA-IN-4
LDHA-IN-4

Artikelnummer: TGM-T3175-10mg

Description: LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis with an active value of 0.093 µM. Target: Dehydrogenase. Smiles: Cc1nc2ccc(NC(=O)CCNC(=O)CCCc3ccc(CC(C(O)=O)C(O)=O)cc3)cc2s1....
Schlagworte: AZ33, AZ-33, LDHA Inhibitor, AZ 33
Anwendung: LDHA inhibitor
CAS 1370290-34-8
MW: 497.56 D
ab 45,00 €
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AZ 33
AZ 33

Artikelnummer: Cay25444-1

AZ 33 is an inhibitor of lactate dehydrogenase A (LDHA, Kd = 0.093 µM, IC50 = 0.5 µM). It is selective for LDHA over LDHB in an NADH competition assay using recombinant enzymes (IC50s = 0.54 and 3.6 µM, respectively). AZ 33 is cell-impermeable and lacks cytotoxicity against HeLa cervical cancer cells (IC50 = >500...
Schlagworte: 2-[[4-[4-[[3-[(2-methyl-6-benzothiazolyl)amino]-3-oxopropyl]amino]-4-oxobutyl]phenyl]methyl]-propanedioic acid
Anwendung: LDHA inhibitor
CAS 1370290-34-8
MW: 497.6 D
ab 44,00 €
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