Zu "136572-09-3" wurden 4 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Irinotecan hydrochloride trihydrate
Artikelnummer: TGM-T0486-100mg
Description: Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1. Target: Autophagy, Topoisomerase. Smiles: O.O.O.Cl.CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OC(=O)N3CCC(CC3)N3CCCCC3)cc12. References: Pavillard V, et al. Cancer Chemother...
| Schlagworte: | Irinotecan HCl Trihydrate, CPT-11 HCl Trihydrate |
| CAS | 136572-09-3 |
| MW: | 677.18 D |
ab 36,00 €
Irinotecan (hydrochloride hydrate)
Artikelnummer: Cay14180-25
Irinotecan, a derivative of the alkaloid camptothecin (Cay-11694), functions as a prodrug that is converted by tissue carboxylesterase to 7-ethyl-10-hydroxycamptothecin, a potent inhibitor of DNA topoisomerase I. Its action is terminated by glucuronidation by UDP glucuronosyl transferase 1A1. Irinotecan demonstrates...
| Schlagworte: | [1,4'-bipiperidine]-1'-carboxylic acid,... |
| Anwendung: | Topoisomerase I inhibitor |
| CAS | 136572-09-3 |
| MW: | 677.2 D |
ab 67,00 €
Irinotecan HCl trihydrate
Artikelnummer: LKT-I6933.10
Inhibitor of the nuclear enzyme topoisomerase I, which is involved in cellular DNA replication and transcription. During replication Topoisomerase I mediates the relaxation of super coiled DNA, and it's inhibition results in breakage of the DNA chain and likely induce apoptosis. Irinotecan is therefore an attractive...
| Schlagworte: | Irinotecan hydrochloride trihydrate |
| Anwendung: | Topoisomerase I inhibitor |
| CAS | 136572-09-3 |
| MW: | 677,2 D |
ab 121,00 €
![Irinotecan, Hydrochloride Salt, Trihydrate ([1,4'-Bipiperidine]-1'-carboxylic Acid (S)-4,11-diethyl-](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "Irinotecan, Hydrochloride Salt, Trihydrate ([1,4'-Bipiperidine]-1'-carboxylic Acid (S)-4,11-diethyl-")
Irinotecan, Hydrochloride Salt, Trihydrate...
Artikelnummer: I8611-02.1
Irinotecan (CPT-11) is a topoisomerase I inhibitor. It is a semisynthetic analog of the natural alkaloid camptothecin and has an active metabolite SN-38 (7-Ethyl-10-hydroxycamptothecin). During the S phase of the cell cycle, camptothecins selectively bind to and stabilize topoisomerase I-DNA complexes, inhibiting...
| CAS | 136572-09-3 |
| MW: | 677.18 |
ab 302,00 €
