Zu "1361414-26-7" wurden 2 Artikel gefunden!
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ML368
Artikelnummer: TGM-T25823-1mg
Description: ML368 is a selective inhibitor of CYP3A4. Target: Others. Smiles: O=C(Nc1ccc(cc1)-c1ccc(cc1)C#N)Nc1ccc(cc1)-c1ccnc2[nH]cnc12. References: Cameron M, Kamenecka T, Madoux F, Chase P, Roush W, Hodder P, Griffin PR. ML368 Identification of Imidazopyridines as Selective Inhibitors of the Cytochrome P450...
| Schlagworte: | SR-9186, ML 368, SR9186, SR 9186, ML-368 |
| Anwendung: | Selective CYP3A4 inhibitor |
| CAS | 1361414-26-7 |
| MW: | 430.46 D |
1.289,00 €
SR 9186
Artikelnummer: Cay13888-1
SR 9186 is an inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 0.011 µM). It is highly selective for CYP3A4 over CYP3A5 (IC50 = 33 µM). SR 9186 inhibits metabolism of midazolam to 1'-hydroxy midazolam, testosterone to 6beta-hydroxy testosterone, and vincristine to vincristine M1 in isolated human liver...
| Schlagworte: | N-(4'-cyano[1,1'-biphenyl]-4-yl)-N'-[4-(3H-imidazo[4,5-b]pyridin-7-yl)phenyl]-urea |
| Anwendung: | Selective CYP3A4 inhibitor |
| CAS | 1361414-26-7 |
| MW: | 430.5 D |
706,00 €
