Zu "1355326-21-4" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Mutant IDH1-IN-1
Artikelnummer: TGM-T2043-100mg
Description: Mutant IDH1-IN-1 is a potent inhibitor of the mutant IDH1 R132 h, exhibiting an IC50 of less than 0.1 µM. Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH). Smiles: Cc1ccccc1C(N(C(=O)Cn1cnc2ccccc12)c1cccc(F)c1)C(=O)NC1CCCCC1. References: Janeta Popovici-Muller, et al. Patent WO2012009678 A1.
| Schlagworte: | IDH1-IN-1 |
| Anwendung: | IDH1 R132H inhibitor |
| CAS | 1355326-21-4 |
| MW: | 498.59 D |
ab 63,00 €
Mutant IDH1-IN-1
Artikelnummer: Cay18394-1
Mutant IDH1-IN-1 is a selective inhibitor of the cancer-associated enzyme mutant isocitrate dehydrogenase 1 (IDH1, Cay-14131) with IC50 values of 42, 4, and 80 nM for homozygous R132H and R132C mutant and heterozygous R132H wild-type enzymes, respectively, for converting alpha-ketoglutarate (alpha-KG) to...
| Schlagworte: | N-[2-(cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-1H-benzimidazole-1-acetamide |
| Anwendung: | IDH1 R132H inhibitor |
| CAS | 1355326-21-4 |
| MW: | 498.6 D |
ab 61,00 €
