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Leniolisib
Artikelnummer: TGM-T5166-100mg
Description: Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kdelta inhibitor (IC50: 11 nM). Target: PI3K, DNA-PK. Smiles: CCC(=O)N1CC[C@@H](C1)Nc1ncnc2CCN(Cc12)c1cnc(OC)c(c1)C(F)(F)F. References: Hoegenauer K, et al. Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K...
| Schlagworte: | CDZ173 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 1354690-24-6 |
| MW: | 450.46 D |
ab 72,00 €
Leniolisib
Artikelnummer: Cay28078-1
Leniolisib is an inhibitor of PI3Kdelta (IC50 = 0.011 µM). It is selective for PI3Kdelta over PI3Kalpha, PI3Kbeta, and PI3Kgamma (IC50s = 0.244, 0.424, and 2.23 µM, respectively). It inhibits phosphorylation of the PI3K target Akt in Rat-1 fibroblasts expressing P13K p110delta with an IC50 value of 0.056 µM....
| Schlagworte: | CDZ 173,... |
| Anwendung: | Immunomodulator, PI3K inhibitor |
| CAS | 1354690-24-6 |
| MW: | 450.5 D |
ab 67,00 €
