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Verinurad
Artikelnummer: TGM-T3994-100mg
Description: Verinurad (RDEA3170) (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia. Target: OAT. Smiles: CC(C)(Sc1ccncc1-c1ccc(C#N)c2ccccc12)C(O)=O. References: Diaz-Torné C, Perez-Herrero N, Perez-Ruiz F. New medications in development for the...
| Schlagworte: | RDEA3170 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 1352792-74-5 |
| MW: | 348.42 D |
ab 40,00 €
Verinurad
Artikelnummer: Cay29667-10
Verinurad is an inhibitor of urate anion transporter 1 (URAT1, IC50 = 0.025 µM for the human transporter). It is selective for human URAT1 over rat URAT1 (IC50 = 41 µM), as well as human organic anion transporter 1 (OAT1) and OAT4 (IC50s = 4.6 and 5.9 µM, respectively).Formal Name:...
| Schlagworte: | 2-[[3-(4-cyano-1-naphthalenyl)-4-pyridinyl]thio]-2-methyl-propanoic acid |
| Anwendung: | URAT1 inhibitor |
| CAS | 1352792-74-5 |
| MW: | 348.4 D |
ab 52,00 €
