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UNC569
Artikelnummer: TGM-T21302-100mg
Description: UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amount of uric acid excreted by gout patients previously classified as under-excretors....
| Schlagworte: | UNC 569 |
| CAS | 1350547-65-7 |
| MW: | 396.5 D |
ab 40,00 €
UNC569
Artikelnummer: Cay22966-5
UNC569 is a potent inhibitor of the TAM family receptor tyrosine kinases Mer, Axl, and Tyro3 (IC50s = 2.9, 37, and 48 nM, respectively). It has antiproliferative activity in vitro against acute lymphoblastic leukemia (ALL) cells (IC50s = 0.5 and 1.2 µM for 697 and Jurkat cell lines, respectively) and inhibits Mer...
| Schlagworte: | 1-[(trans-4-aminocyclohexyl)methyl]-N-butyl-3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine |
| Anwendung: | MERTK inhibitor |
| CAS | 1350547-65-7 |
| MW: | 396.5 D |
ab 52,00 €
