Zu "1349796-36-6" wurden 4 Artikel gefunden!
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PI3K-IN-1
Artikelnummer: TGM-T1826-100mg
Description: PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110gamma , also inhibits DNA-PK and mTOR. Target: PI3K, DNA-PK. Smiles: COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(NC(=O)c3ccc(OC)c(C)c3)cc2)cc(OC)c1. References: Garcia-Echeverria C, et al. Oncogene, 2008, 27(41), 5511-5526.
| Schlagworte: | SAR245409, XL765, Voxtalisib Analogue, Voxtalisib (SAR245409, XL765) Analogue |
| Anwendung: | PI3K inhibitor |
| CAS | 1349796-36-6 |
| MW: | 599.66 D |
ab 33,00 €
XL147 analog 2
Artikelnummer: Cay16299-1
XL147 analog 2 is an analog of XL147 (Cay-18011).Formal Name: N-[4-[[[3-[(3,5-dimethoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-3-methoxy-4-methyl-benzamide. CAS Number: 1349796-36-6. Molecular Formula: C31H29N5O6S. Formula Weight: 599.7. Purity: >95%. Formulation: (Request formulation change), A...
| Schlagworte: | SAR245409, Voxtalisib,... |
| Anwendung: | PI3K inhibitor |
| CAS | 1349796-36-6 |
| MW: | 599.7 D |
ab 61,00 €
XL-765
Artikelnummer: SYN-1137-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. XL765 is active against class I PI3K (IC(50) = 39, 113, 9 and 43nM for p110alpha, beta, gamma and delta, respectively). XL765 also inhibits DNA-PK (IC(50) = 150nM) and mTOR (IC(50) = 157nM. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
| Schlagworte: | SAR-245409 |
| Anwendung: | PI3K / DNA-PK / mTOR inhibitor |
| CAS | 1349796-36-6 |
| MW: | 599,7 D |
ab 193,00 €
SAR245409
Artikelnummer: LKT-S0269.1
SAR245409 is a pyridopyrimidinone derivative that inhibits PI3K and mTOR. This compound exhibits anticancer chemotherapeutic activity and shows benefit in clinical trials as a potential treatment for advanced solid tumors. SAR245409 inhibits cell proliferation and tumor growth in a variety of cancer models.
| Anwendung: | PI3K inhibitor |
| CAS | 1349796-36-6 |
| MW: | 599.66 D |
ab 109,00 €
