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GSK343
Artikelnummer: TGM-T6059-100mg
Description: GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity against other histone methyltransferases. Target: Histone Methyltransferase, Autophagy. Smiles:...
| Anwendung: | Cell-permeable EZH2 inhibitor |
| CAS | 1346704-33-3 |
| MW: | 541.69 D |
ab 54,00 €
GSK343
Artikelnummer: Cay14094-1
The histone H3 lysine 27 (H3K27) methyltransferase EZH2 plays an important role in regulating gene expression, and its aberrant activity is linked to the onset and progression of cancer. GSK343 is a cell-permeable EZH2 inhibitor (IC50 = 4 nM) that is 60-fold selective over EZH1 and >1,000-fold selective over other...
| Schlagworte: | N-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1... |
| Anwendung: | Cell-permeable EZH2 inhibitor |
| CAS | 1346704-33-3 |
| MW: | 541.7 D |
ab 52,00 €
GSK-343
Artikelnummer: LKT-G7442.1
GSK-343 is an inhibitor of enhancer of zeste homolog 2 (EZH2) histone methyltransferase (HMT). GSK-343 exhibits anticancer activity, inhibiting cell invasion and cell growth in epithelial ovarian cancer cells.
| Anwendung: | Cell-permeable EZH2 inhibitor |
| CAS | 1346704-33-3 |
| MW: | 541.69 D |
ab 81,00 €
