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GSK621
GSK621

Artikelnummer: TGM-T6854-100mg

Description: GSK621 is a specific and potent AMPK activator. Target: Autophagy, Apoptosis, AMPK. Smiles: COc1cccc(c1)-n1c(=O)[nH]c2cc(Cl)n(-c3ccc(cc3)-c3cccc(OC)c3O)c2c1=O. References: Sujobert P, et al. Cell Rep. 2015, 11(9), 1446-1457.
Anwendung: AMPK activator
CAS 1346607-05-3
MW: 489.91 D
ab 50,00 €
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GSK621
GSK621

Artikelnummer: Cay19155-5

GSK621 is an activator of AMP-activated protein kinase (AMPK). It has been shown to increase phosphorylation at AMPKalpha T172, a marker of AMPK activation, in both acute myeloid leukemia (AML) cell lines and primary AML samples. GSK621 is reported to reduce the proliferation of AML cell lines (IC50s = 13-30 µM),...
Schlagworte: 6-chloro-5-(2'-hydroxy-3'-methoxy[1,1'-biphenyl]-4-yl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione
Anwendung: AMPK activator
CAS 1346607-05-3
MW: 489.9 D
ab 77,00 €
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