Zu "1345982-69-5" wurden 2 Artikel gefunden!
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Linerixibat
Artikelnummer: TGM-T3978-10mg
Description: Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM) that can lower glucose in an animal model of type 2 diabetes and demonstrates excellent developability properties. Target: HBV. Smiles:...
| Schlagworte: | Iinerixibat, GSK2330672 |
| Anwendung: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
| CAS | 1345982-69-5 |
| MW: | 546.68 D |
ab 76,00 €
GSK2330672
Artikelnummer: Cay23843-1
GSK2330672 is an inhibitor of the sodium/bile acid and sulfated solute cotransporter (ASBT, IC50s = 42, 2.1, and 1.9 nM for human, mouse, and rat ASBT, respectively). In vivo, GSK2330672 (0.05 mg/kg) stimulates fecal bile acid secretion, reduces hemoglobin A1c (HbA1c) and plasma glucose levels, and increases total...
| Schlagworte: | 3-[[[(3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4-benzothiazepin-8-yl]methyl]amino]-penta... |
| Anwendung: | SLC10A2 / ASBT inhibitor |
| CAS | 1345982-69-5 |
| MW: | 546.7 D |
ab 150,00 €
