Zu "1345847-93-9" wurden 3 Artikel gefunden!
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Altiratinib
Artikelnummer: TGM-T2054-100mg
Description: Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor, effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with an HGF antagonist in vitro. Target: c-Met/HGFR, FLT, Tie-2, Trk receptor, VEGFR. Smiles:...
| Schlagworte: | DCC-2701 |
| Anwendung: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 1345847-93-9 |
| MW: | 510.46 D |
ab 48,00 €
Altiratinib
Artikelnummer: Cay18777-5
Altiratinib is a multiple kinase inhibitor, blocking Met, Tie2, VEGF2, TrkA, TrkB, and TrkC with IC50 values of 2.7, 8.0, 9.2, 0.85, 4.6, and 0.83 nM, respectively. It also inhibits several mutant Met isoforms at nanomolar concentrations. Altiratinib inhibits the proliferation of several cancer cell lines in vitro...
| Schlagworte: | N-[4-[[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]oxy]-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Anwendung: | MET / TIE2 / VEGFR2 inhibitor |
| CAS | 1345847-93-9 |
| MW: | 510.5 D |
ab 44,00 €
Altiratinib
Artikelnummer: LKT-A4777.5
c-MET, Tie-2, VEGFR inhibitor.
| Schlagworte: | DCC-2701, DP-5164,... |
| Anwendung: | MET / TIE2 / VEGFR2 inhibitor |
| CAS | 1345847-93-9 |
| MW: | 510.46 D |
ab 117,00 €
