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BP-1-102
Artikelnummer: TGM-T3708-100mg
Description: BP-1-102 is an orally active, effective, and specific STAT3 inhibitor that binds Stat3 (Kd: 504 nM), blocks Stat3-phosphotyrosine (pTyr) peptide interactions and Stat3 activation (4-6.8 µM), and selectively inhibits the migration, survival, growth, and invasion of Stat3-dependent tumor cells. The...
| Anwendung: | STAT3 inhibitor |
| CAS | 1334493-07-0 |
| MW: | 626.59 D |
ab 33,00 €
BP-1-102
Artikelnummer: Cay28368-5
BP-1-102 is an inhibitor of STAT3. It binds to STAT3 (Kd = 504 nM) and inhibits STAT3 binding to an IL-6R/gp130 peptide in a fluorescence polarization assay (IC50 = 4.1 µM). BP-1-102 (10-30 µM) decreases viability and proliferation of STAT3-dependent NIH3T3/v-Src, MDA-MB-231, PANC-1, DU145 and A549 cancer cells, but...
| Schlagworte: | 4-[[(4-cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-2-hydroxy-benzoic acid |
| Anwendung: | STAT3 inhibitor |
| CAS | 1334493-07-0 |
| MW: | 626.6 D |
ab 163,00 €
