Zu "1333207-63-8" wurden 2 Artikel gefunden!
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SAR7334 hydrochloride
Artikelnummer: TGM-T12849L-100mg
Description: SAR7334 hydrochloride, a potent and specific inhibitor of TRPC6 (IC50 of 7.9 nM), effectively targets and inhibits the TRPC6 channel. Target: Others. Smiles: Cl.Cl.N[C@@H]1CCCN(C1)[C@@H]1Cc2ccccc2[C@H]1Oc1ccc(cc1Cl)C#N. References: Ilatovskaya DV, et al. The Role of Angiotensin II in Glomerular Volume...
| Anwendung: | TRPC6 blocker |
| CAS | 1333207-63-8 |
| MW: | 440.79 D |
ab 78,00 €
SAR7334 (hydrochloride)
Artikelnummer: Cay28292-1
SAR7334 is a transient receptor potential canonical 6 (TRPC6) channel blocker (IC50 = 7.9 nM). It is selective for TRPC6 over TRPC4 and TRPC5 (IC50s = 282 and 226 nM, respectively). SAR7334 (0.2-1 µM) blocks TRPC6-dependent hypoxia-induced vasoconstriction in isolated perfused and ventilated mouse lung. It also...
| Schlagworte: | 4-[[(1R,2R)-2-[(3R)-3-amino-1-piperidinyl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloro-benzonitrile, dihydrochloride |
| Anwendung: | TRPC6 blocker |
| CAS | 1333207-63-8 |
| MW: | 440.8 D |
ab 52,00 €
