Zu "1320346-97-1" wurden 2 Artikel gefunden!
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GLPG0187
Artikelnummer: TGM-T4259-100mg
Description: GLPG0187, a broad spectrum integrin receptor antagonist, inhibits alphavbeta1-integrin (IC50: 1.3 nM). Target: Integrin. Smiles: COc1ccc(cc1)S(=O)(=O)N[C@@H](CNc1nc(C)nc(N2CCC(CC2)C2=CC=C3CCCN=C3N2)c1C)C(O)=O. References: van der Horst G, et al. Targeting of alpha(v)-integrins in stem/progenitor cells...
| Anwendung: | ITGAV antagonist |
| CAS | 1320346-97-1 |
| MW: | 595.71 D |
ab 40,00 €
GLPG0187
Artikelnummer: Cay21792-5
GLPG0187 is a nonpeptide antagonist of alphanu integrin receptors (IC50s = 1.2-3.7 nM). It inhibits osteoclastogenesis, bone resorption, and angiogenesis in vitro and in vivo in mice, which are all hallmarks of bone marrow invasion in metastatic prostate cancer. GLPG0187 reduces epithelial-mesenchymal transition...
| Schlagworte: | 3-[[2,5-dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)s... |
| Anwendung: | ITGAV antagonist |
| CAS | 1320346-97-1 |
| MW: | 595.7 D |
ab 67,00 €
