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TMP195
Artikelnummer: TGM-T3983-100mg
Description: TMP195 (TFMO 2) is a selective class IIa histone deacetylase (HDAC) inhibitor. Target: HDAC. Smiles: CC(C)(CNC(=O)c1cccc(c1)-c1noc(n1)C(F)(F)F)c1coc(n1)-c1ccccc1. References: Lobera M., et al. Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group. Nat Chem Biol. 2013...
| Schlagworte: | TFMO 2, TMP 195 |
| Anwendung: | Class IIa HDAC inhibitor |
| CAS | 1314891-22-9 |
| MW: | 456.42 D |
ab 67,00 €
TMP-195
Artikelnummer: Cay23242-5
TMP-195 is an inhibitor of class IIa histone deacetylases (HDACs, Kis = 59, 60, 26, and 15 nM for HDAC4, 5, 7, and 9, respectively). It is selective for class IIa HDACs over class I and class IIb HDACs (Kis = 10-43 µM for HDAC1-3, 6, 9, and 10-11). TMP-195 blocks accumulation of chemoattractant chemokine ligand 2...
| Schlagworte: | N-[2-methyl-2-(2-phenyl-4-oxazolyl)propyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-benzamide |
| Anwendung: | Class IIa HDAC inhibitor |
| CAS | 1314891-22-9 |
| MW: | 456.4 D |
ab 44,00 €
