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TMP269
Artikelnummer: TGM-T1857-100mg
Description: TMP269 is an effective, specific class IIa HDAC inhibitor for HDAC4 (IC50: 157 nM), HDAC5 (IC50: 97 nM), HDAC7 (IC50: 43 nM), and HDAC9 (IC50: 23 nM), respectively. Target: HDAC. Smiles: FC(F)(F)c1nc(no1)-c1cccc(c1)C(=O)NCC1(CCOCC1)c1nc(cs1)-c1ccccc1. References: Lobera M, et al. Nat Chem Biol. 2013,...
| Anwendung: | Cell-permeable class IIa HDAC inhibitor |
| CAS | 1314890-29-3 |
| MW: | 514.52 D |
ab 65,00 €
TMP269
Artikelnummer: Cay17738-1
While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which include HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. TMP269 is a cell-permeable inhibitor...
| Schlagworte: | N-[[tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-benzamide |
| Anwendung: | Cell-permeable class IIa HDAC inhibitor |
| CAS | 1314890-29-3 |
| MW: | 514.5 D |
ab 52,00 €
TMP-269
Artikelnummer: LKT-T5060.5
HDAC inhibitor.
| Anwendung: | HDAC inhibitor |
| CAS | 1314890-29-3 |
| MW: | 514.52 D |
ab 177,00 €
