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PF-4693627
Artikelnummer: TGM-T16504-10mg
Description: PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM). It is used for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA). Target: Prostaglandin Receptor. Smiles:...
| Anwendung: | mPGES-1 inhibitor |
| CAS | 1312815-93-2 |
| MW: | 502.43 D |
ab 91,00 €
PF-4693627
Artikelnummer: Cay22768-1
PF-4693627 is an orally bioavailable inhibitor of microsomal prostaglandin E (PGE) synthase-1 (mPGES-1, IC50 = 3 nM). It is selective for mPGES-1 over PGDS, TXAS, and 5-LO in HWB-1483 cells, which have IC50 values greater than 50 µM, as well as COX-2 in fetal fibroblasts (IC50 = >10 µM). PF-4693627 inhibits...
| Schlagworte: | 1-[5-chloro-6-(4-chlorophenyl)-2-benzoxazolyl]-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]-4-piperidinecarboxamide |
| Anwendung: | mPGES-1 inhibitor |
| CAS | 1312815-93-2 |
| MW: | 502.4 D |
ab 50,00 €
