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NSC624206
Artikelnummer: TGM-T12265-1mg
Description: NSC624206 is a ubiquitin E1 (UBA1) inhibitor(IC50 of ~9 µM). Target: Others. Smiles: Cl.CCCCCCCCCC NCCSSCc1ccc(Cl)cc1. References: Dana Ungermannova, et al. Identification and Mechanistic Studies of a Novel Ubiquitin E1 Inhibitor. J Biomol Screen . 2012 Apr,17(4):421-34.
| Anwendung: | Ubiquitin-activating enzyme (E1) inhibitor |
| CAS | 13116-77-3 |
| MW: | 410.51 D |
ab 77,00 €
NSC 624206
Artikelnummer: Cay20569-1
NSC 624206 is an inhibitor of ubiquitin-activating enzyme (E1) that specifically blocks ubiquitin-thioester formation (IC50 = 13 µM) but has no effect on ubiquitin adenylation. Through this action, NSC 624206 prevents the ubiquitination and degradation of the tumor suppressor protein p27 in vitro.Formal Name:...
| Schlagworte: | N-[2-[[(4-chlorophenyl)methyl]dithio]ethyl]-1-decanamine, monohydrochloride |
| Anwendung: | Ubiquitin-activating enzyme (E1) inhibitor |
| CAS | 13116-77-3 |
| MW: | 410.5 D |
ab 44,00 €
