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H-89 (hydrochloride)
Artikelnummer: Cay10010556-10
Protein kinase A (PKA) regulates multiple signal transduction events via protein phosphorylation and is integral to all cellular responses involving the cyclic AMP second messenger system. H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM in standard...
| Schlagworte: | 5-Isoquinolinesulfonamide, Protein Kinase Inhibitor H-89,... |
| Anwendung: | PKA inhibitor |
| CAS | 130964-39-5 |
| MW: | 519.3 D |
ab 67,00 €
H-89 dihydrochloride
Artikelnummer: TGM-T6250-100mg
Description: H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA, IC50: 0.14 µM, Ki: 48 nM). Target: Autophagy, S6 Kinase, PKA. Smiles: Cl.Cl.Brc1ccc(\C=C\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1. References: Chijiwa T, et al. Inhibition of forskolin-induced neurite outgrowth...
| Schlagworte: | 5-Isoquinolinesulfonamide, H 89 2HCl, Protein kinase inhibitor H-89 dihydrochloride |
| Anwendung: | PKA inhibitor |
| CAS | 130964-39-5 |
| MW: | 519.28 D |
ab 34,00 €
