Zu "129830-38-2" wurden 4 Artikel gefunden!
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Y-27632 (hydrochloride)
Artikelnummer: Cay10005583-10
The ROCK family of Rho-associated serine-threonine protein kinases is known to play an important role in Rho-mediated cell adhesion and smooth muscle contraction. Y-27632 is a potent, ATP-competitive inhibitor of ROCKs including p160ROCK (Ki = 140 nM) and ROCK2 (IC50 = 800 nM). It also inhibits PRK2 with an IC50...
| Schlagworte: | 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-trans-cyclohexanecarboxamide, dihydrochloride |
| Anwendung: | ROCK inhibitor |
| CAS | 129830-38-2 |
| MW: | 320.3 D |
ab 78,00 €
Y27632 dihydrochloride
Artikelnummer: LKT-Y1000.25
Y27632 is a selective inhibitor of Rho-associated protein kinase (ROCK), Y27632 binds to the catalytic site of ROCK, preventing binding of Ras-related GTPase Rho A, which is involved in actin cytoskeleton reorganization, cell adhesion, and cell migration. Y27632 inhibits downstream endothelin and TGF- -related...
| Anwendung: | ROCK inhibitor |
| CAS | 129830-38-2 |
| MW: | 320.26 D |
ab 128,00 €
Y-27632 . dihydrochloride
Artikelnummer: AG-CR1-3564-M010
Potent, cell permeable, selective and ATP-competitive Rho-associated protein kinases inhibitor, including p160ROCK, ROCK-II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stellate cell growth inhibition. Antinociceptive. Blocks...
| Schlagworte: | Y-27632 - 2HCL, (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride |
| Anwendung: | ROCK kinase inhibitor |
| CAS | 129830-38-2 |
| MW: | 320.2 D |
ab 55,00 €
Y-27632 dihydrochloride
Artikelnummer: TGM-T1725-10mg
Description: Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells. Target: Apoptosis, ROCK. Smiles: Cl.Cl.C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc1ccncc1....
| Schlagworte: | Y-27632 2HCl |
| Anwendung: | ROCK kinase inhibitor |
| CAS | 129830-38-2 |
| MW: | 320.26 D |
ab 40,00 €
