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Darolutamide
Artikelnummer: TGM-T6915-25mg
Description: Darolutamide (BAY-1841788) is an androgen receptor (AR) antagonist that blocks AR nuclear translocation (Ki: 11 nM). Target: Androgen Receptor. Smiles: C[C@@H](Cn1ccc(n1)-c1ccc(C#N)c(Cl)c1)NC(=O)c1cc([nH]n1)C(C)O. References: Moilanen AM, et al. Sci Rep. 2015, 5:12007. doi: 10.1038/srep12007.
| Schlagworte: | ODM-201, BAY-1841788 |
| Anwendung: | Targets androgen receptor (AR, NR3C4) |
| CAS | 1297538-32-9 |
| MW: | 398.85 D |
ab 45,00 €
ODM-201
Artikelnummer: Cay25643-1
ODM-201 is an androgen receptor (AR) antagonist (Ki = 11 nM). It inhibits AR transactivation in U2OS osteosarcoma cells expressing human wild-type and mutant ARs (IC50s = 65, 66, 1,500, and 1,782 nM for wild-type, ARF876L, ARW741L, and ART877A, respectively). ODM-201 prevents androgen-induced AR nuclear...
| Schlagworte: | BAY 1841788,... |
| Anwendung: | Androgen receptor (AR) antagonist |
| CAS | 1297538-32-9 |
| MW: | 398.9 D |
ab 61,00 €
