Zu "1295298-26-8" wurden 2 Artikel gefunden!
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CCR1 antagonist 8
Artikelnummer: TGM-T14899-100mg
Description: CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM in Ca2+ flux assay). Target: CCR. Smiles: CS(=O)(=O)c1cc(ccn1)C1(CC1)NC(=O)c1cncc2n(ncc12)-c1ccc(F)cc1. References: Harcken C, et al. Identification of novel azaindazole CCR1 antagonist clinical candidates. Bioorg...
| Anwendung: | CCR1 antagonist |
| CAS | 1295298-26-8 |
| MW: | 451.47 D |
ab 1.059,00 €
BI-639667
Artikelnummer: Cay41523-1
BI-639667 is a chemokine (C-C motif) receptor 1 (CCR1) antagonist. It inhibits calcium flux induced by chemokine (C-C motif) ligand 3 (CCL3) in cells expressing CCR1 (IC50 = 2 nM). BI-639667 also inhibits RANTES-induced chemotaxis in THP-1 cells (IC50 = 2 nM).Formal Name:...
| Schlagworte: | 1-(4-fluorophenyl)-N-[1-[2-(methylsulfonyl)-4-pyridinyl]cyclopropyl]-1H-pyrazolo[3,4-c]pyridine-4-carboxamide |
| Anwendung: | CCR1 antagonist |
| CAS | 1295298-26-8 |
| MW: | 451.5 D |
ab 85,00 €
