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Rhosin hydrochloride
Artikelnummer: TGM-T16745-100mg
Description: Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride causes cell apoptosis. Target: Rho,...
| Anwendung: | Rho-GEF protein-protein interaction inhibitor |
| CAS | 1281870-42-5 |
| MW: | 431.318 D |
ab 158,00 €
Rhosin (hydrochloride)
Artikelnummer: Cay36415-5
Rhosin is an inhibitor of the protein-protein interaction between Rho and guanine nucleotide exchange factors (GEFs). It inhibits RhoA activity when used at concentrations of 10 and 30 µM and selectively reduces the number and size of MCF-7 breast cancer cell mammospheres over MCF-10A non-cancerous cell...
| Schlagworte: | G04, 2-(6-quinoxalinylmethylene)hydrazide, D-Tryptophan, monohydrochloride |
| Anwendung: | Rho-GEF protein-protein interaction inhibitor |
| CAS | 1281870-42-5 |
| MW: | 394.9 D |
ab 76,00 €
