Zu "1279713-77-7" wurden 2 Artikel gefunden!
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CU-CPT4a
Artikelnummer: Cay30951-500
CU-CPT4a is a toll-like receptor 3 (TLR3) antagonist (IC50 = 3.44 µM). It is selective for TLR3 over TLR4, TLR2/6, TLR1/2, and TLR7 at 27 µM. CU-CPT4a inhibits dsRNA binding to TLR3 with a Ki value of 2.96 µM in a fluorescence anisotropy assay. It decreases poly(I:C)-induced production of TNF-alpha and IL-1beta in...
| Schlagworte: | N-[(3-chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine |
| Anwendung: | TLR3 antagonist |
| CAS | 1279713-77-7 |
| MW: | 377.8 D |
ab 92,00 €
TLR3-IN-1
Artikelnummer: TGM-T22698-100mg
Description: TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 µM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-alpha and IL-1beta in whole cells. Target: TLR. Smiles: OC(=O)[C@@H](Cc1ccccc1)NC(=O)c1sc2cc(F)ccc2c1Cl....
| Schlagworte: | CU CPT 4a |
| Anwendung: | TLR3 antagonist |
| CAS | 1279713-77-7 |
| MW: | 377.82 D |
ab 48,00 €
