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KN-62
Artikelnummer: TGM-T2694-100mg
Description: KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 µM. Target: Autophagy, P2X Receptor, CaMK. Smiles: O=C([C@H](Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)NCS(=O)(=O)c1cccc2cnccc12)N1CCN(CC1)c1ccccc1. References: Tokumitsu H, et al. J Biol Chem. 1990,...
| CAS | 127191-97-3 |
| MW: | 721.84 D |
ab 31,00 €
KN-62
Artikelnummer: Cay13318-5
KN-62 is a selective, cell permeable inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII, IC50 = 900 nM). It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).Formal Name:...
| Schlagworte: | 5-isoquinolinesulfonic acid,... |
| Anwendung: | CAMKII inhibitor |
| CAS | 127191-97-3 |
| MW: | 721.9 D |
ab 67,00 €
