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NVP-2
Artikelnummer: TGM-T16363-100mg
Description: NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC50: 0.584 µM, 0.706 µM, and 0.605 µM,...
| Anwendung: | Cdk9/cyclin T1 complex inhibitor |
| CAS | 1263373-43-8 |
| MW: | 513.07 D |
ab 49,00 €
NVP-2
Artikelnummer: Cay34725-1
NVP-2 is an inhibitor of the Cdk9/cyclin T1 complex (IC50 = 50s = 0.584->10 µM), as well as over a panel of 468 kinases at 1 µM. NVP-2 (250 nM) inhibits the proliferation of, and induces apoptosis in, MOLT-4 human acute lymphoblastic leukemia cells.Formal Name:...
| Schlagworte: | 4-[[[5'-chloro-2'-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino][2,4'-bipyridin]-6-yl]amino]methyl]tetra... |
| Anwendung: | Cdk9/cyclin T1 complex inhibitor |
| CAS | 1263373-43-8 |
| MW: | 513.1 D |
ab 61,00 €
