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Spautin-1
Artikelnummer: TGM-T1937-100mg
Description: Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03 µM. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 µM. Target: Apoptosis, DUB, Autophagy. Smiles: Fc1ccc(CNc2ncnc3ccc(F)cc23)cc1. References:...
| Schlagworte: | Spautin 1 |
| Anwendung: | Autophagy inhibitor, USP10 / USP13 inhibitor |
| CAS | 1262888-28-7 |
| MW: | 271.26 D |
ab 33,00 €
Spautin-1
Artikelnummer: Cay17769-5
Spautin-1 is an autophagy inhibitor, inducing cell death in human breast cancer Bcap-37 cells grown in glucose-free media (EC50 = ~1.25 µM). It does not significantly affect the viability of Bcap-37 cells grown in complete media. Spautin-1 promotes the degradation of Vps34 PI3K complex by inhibiting the...
| Schlagworte: | 6-fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine |
| Anwendung: | Autophagy inhibitor, USP10 / USP13 inhibitor |
| CAS | 1262888-28-7 |
| MW: | 271.3 D |
ab 43,00 €
