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O-304
Artikelnummer: TGM-T7362-100mg
Description: O-304 is a pan-activator of AMP-activated protein kinase (AMPK). Target: AMPK. Smiles: Clc1ccc(Cn2sc(NC(=O)c3ccc(Cl)cc3)nc2=O)cc1. References: Steneberg, Pär, Lindahl E , Dahl U , et al. PAN-AMPK activator O304 improves glucose homeostasis and microvascular perfusion in mice and type 2 diabetes...
| Anwendung: | AMPK activator |
| CAS | 1261289-04-6 |
| MW: | 380.25 D |
ab 59,00 €
O-304
Artikelnummer: Cay26186-1
O-304 is a pan-activator of AMP-activated protein kinase (AMPK). It increases levels of phosphorylated AMPK (pAMPK) without reducing cellular ATP. O-304 suppresses dephosphorylation of AMPKalpha, AMPKbeta, and AMPKgamma trimers at threonine 172 (T172) mediated by protein phosphatase 2C (PP2C) without inhibiting PP2C...
| Schlagworte: | 4-chloro-N-[2-[(4-chlorophenyl)methyl]-2,3-dihydro-3-oxo-1,2,4-thiadiazol-5-yl]-benzamide |
| Anwendung: | AMPK activator |
| CAS | 1261289-04-6 |
| MW: | 380.2 D |
ab 80,00 €
