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TCS 21311
Artikelnummer: TGM-T17019-1mg
Description: TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKCalpha, PKCtheta, and GSK3beta (IC50s: 13, 68, and 3 nM, respectively). It displays >100-fold selectivity over JAK1, JAK2, and TYK2. Target: JAK, GSK-3, PKC. Smiles:...
| Schlagworte: | NIBR3049 |
| Anwendung: | JAK3 inhibitor |
| CAS | 1260181-14-3 |
| MW: | 526.51 D |
98,00 €
TCS 21311
Artikelnummer: Cay30063-5
TCS 21311 is an inhibitor of JAK3 (IC50 = 8 nM in an enzyme assay). It is selective for JAK3 over JAK1, JAK2, and tyrosine kinase 2 (TYK2, IC50s = 1,017, 2,550, and 8,055 nM, respectively) but does inhibit glycogen synthase kinase 3beta (GSK-3beta), PKCalpha, and PKCtheta (IC50s = 13, 68, and 3 nM, respectively)....
| Schlagworte: | NIBR3049,... |
| Anwendung: | JAK3 inhibitor |
| CAS | 1260181-14-3 |
| MW: | 526.5 D |
ab 78,00 €
