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Atorvastatin lactone
Artikelnummer: TGM-T14342-100mg
Description: Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Target: HMG-CoA Reductase. Smiles: CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1. References: Valesky RJ, et al....
| Anwendung: | Atorvastatin (HMG-CoA reductase inhibitor) prodrug |
| CAS | 125995-03-1 |
| MW: | 540.62 D |
ab 33,00 €
Atorvastatin lactone
Artikelnummer: Cay20951-1
Atorvastatin lactone is an active metabolite of the HMG-CoA reductase inhibitor atorvastatin. It is formed from atorvastatin by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A3 and UGT1A1 in insect cell-derived supersomes expressing the human enzymes, and hydrolyzes to form atorvastatin in human serum at room...
| Schlagworte: | 5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole... |
| Anwendung: | Atorvastatin (HMG-CoA reductase inhibitor) prodrug |
| CAS | 125995-03-1 |
| MW: | 540.6 D |
ab 43,00 €
