Zu "1254053-43-4" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Gilteritinib
Artikelnummer: TGM-T4409-100mg
Description: Gilteritinib (ASP2215) is a potent inhibitor of FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preclinical studies, gilteritinib demonstrated strong antileukemic and antitumor effects. Gilteritinib is currently in several Phase 3...
| Schlagworte: | ASP2215 |
| Anwendung: | Targets fms-related tyrosine kinase 3 [EC:2.7.10.1] (FLT3, FLK2, CD135) |
| CAS | 1254053-43-4 |
| MW: | 552.71 D |
ab 34,00 €
Gilteritinib
Artikelnummer: Cay21503-1
Gilteritinib is an inhibitor of FMS-related tyrosine kinase 3 (FLT3, IC50 = 5 nM for the wild-type enzyme). It inhibits mutant forms of FLT3, including FLT3 with the internal tandem duplication mutation (FLT3-ITD), FLT3-ITD expressing the F691L mutation, and FLT3 with various tyrosine kinase domain mutations...
| Schlagworte: | ASP2215,... |
| Anwendung: | FLT3 / AXL inhibitor |
| CAS | 1254053-43-4 |
| MW: | 552.7 D |
ab 43,00 €
