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KS176
Artikelnummer: TGM-T3581-100mg
Description: KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter, exhibiting no inhibitory activity against P-gp or MRP1. Target: BCRP, Potassium Channel. Smiles: OCCc1ccc(NC(=O)c2ccccc2NC(=O)c2ccc(cc2)[N+]([O-])=O)cc1. References: Pick A, et al. Specific...
| Anwendung: | ABCG2 inhibitor |
| CAS | 1253452-78-6 |
| MW: | 405.4 D |
ab 37,00 €
KS-176
Artikelnummer: Cay22201-1
KS-176 is a selective inhibitor of breast cancer resistance protein (BRCP, IC50 = 1.39 µM) with no activity against P-glycoprotein (P-gp) or multidrug resistance-associated protein 1 (MRP1). It acts as a non-competitive inhibitor whose potency is increased by imatinib binding. KS-176 does not reduce cell viability...
| Schlagworte: | N-[4-(2-hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]-benzamide |
| Anwendung: | ABCG2 inhibitor |
| CAS | 1253452-78-6 |
| MW: | 405.4 D |
ab 43,00 €
