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Bayer 18
Artikelnummer: Cay41124-1
Bayer 18 is a tyrosine kinase 2 (TYK2) inhibitor (IC50 = 18.7 nM). It is selective for TYK2 over JAK2, cyclin-dependent kinase 2 (Cdk2), and VEGFR2 (IC50s = 2,000, 1,790, and 3,520 nM, respectively).Formal Name:...
| Schlagworte: | N-(1,1-dimethylethyl)-N'-[3-[[5-fluoro-4-[(2-hydroxy-1,1-dimethylethyl)amino]-2-pyrimidinyl]amino]phenyl]-urea |
| Anwendung: | TYK2 inhibitor |
| CAS | 1251752-12-1 |
| MW: | 390.5 D |
ab 126,00 €
Bayer-18
Artikelnummer: SYN-1130-M001
Soluble in DMSO. Bayer-18 is a selective TYK2 inhibitor, with an IC(50) of 18.7nM on TYK2 as measured by TYK2 HTRF assays. The compound shows 1000 fold selectivity against JAK2, CDK and KDR kinases in similar HTRF assays. Target: TYK2 , Kinase Group: RTK , Substrate: Tyrosine
| Schlagworte: | Bayer18 |
| Anwendung: | TYK2 inhibitor |
| CAS | 1251752-12-1 |
| MW: | 390,5 D |
ab 293,00 €
