Zu "125079-83-6" wurden 2 Artikel gefunden!
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CU-CPT-8m
Artikelnummer: TGM-T7347-100mg
Description: CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM). Target: TLR. Smiles: Cc1cccc(c1)-c1ccnc2c(cnn12)C(N)=O. References: Zhang S , Hu Z , Tanji H , et al. Small-molecule inhibition of TLR8 through stabilization of its resting state[J]. Nature Chemical...
| Schlagworte: | TLR8-specific antagonist |
| Anwendung: | TLR8 antagonist |
| CAS | 125079-83-6 |
| MW: | 252.27 D |
ab 48,00 €
CU-CPT8m
Artikelnummer: Cay25349-1
CU-CPT8m is an antagonist of toll-like receptor 8 (TLR8, Kd = 220 nM, IC50 = 67 nM in a reporter assay). It is selective for TLR8 over a panel of all other human TLRs when used at a concentration of 1 µM. CU-CPT8m (1 µM) inhibits increases in TNF-alpha and IL-8 mRNA expression induced by the TLR8 agonist R-848...
| Schlagworte: | 7-(3-methylphenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxamide |
| Anwendung: | TLR8 antagonist |
| CAS | 125079-83-6 |
| MW: | 252.3 D |
ab 43,00 €
