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TK05
Artikelnummer: TGM-T13165-100mg
Description: TK05 is a potent and selective leukotriene C4 synthase (LTC4S) inhibitor with an IC50 of 95 nM. Target: Others. Smiles: COc1ccc(cc1)C(=O)c1ccc(cc1C(O)=O)C(=O)c1ccc(cn1)N(CC1CC1)c1ccc(Cl)cc1. References: Kleinschmidt TK, et al. Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human...
| CAS | 1245734-61-5 |
| MW: | 540.99 D |
ab 1.520,00 €
TK05
Artikelnummer: Cay19793-1
TK05 is an inhibitor of leukotriene C4 (LTC4) synthase (IC50 = 95 nM). It is selective for LTC4 synthase over microsomal prostaglandin E synthase-1 (mPGES-1), microsomal glutathione S-transferase 2 (GST2), and 5-lipoxygenase (5-LO) at 10 µM. TK05 (1 µM) inhibits LTC4 synthase in Mono-Mac-6 leukemia cells and...
| Schlagworte: | 5-[[5-[(4-chlorophenyl)(cyclopropylmethyl)amino]-2-pyridinyl]carbonyl]-2-(4-methoxybenzoyl)-benzoic acid |
| Anwendung: | LTC4 synthase inhibitor |
| CAS | 1245734-61-5 |
| MW: | 541 D |
ab 153,00 €
