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Wnt-C59
Wnt-C59

Artikelnummer: Cay16644-1

Porcupine (PORCN) is a membrane bound O-acyltransferase that mediates palmitoylation of Wnt family proteins. This step is required for secretion and biologic activity of Wnt proteins, which have roles in embryonic development and cancer. Wnt-C59 is a potent inhibitor of PORCN, as measured by prevention of Wnt3A...
Schlagworte: PORCN Inhibitor II, 4-(2-methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]-benzeneacetamide
Anwendung: Porcupine inhibitor
CAS 1243243-89-1
MW: 379.5 D
ab 61,00 €
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C59
C59

Artikelnummer: LKT-C0800.1

C59 is a PORCN inhibitor that exhibits anticancer chemotherapeutic activity, inhibiting the progression of mammary tumors in vivo by downregulating Wnt signaling.
Schlagworte: Wnt-C59
Anwendung: PORCN inhibitor
CAS 1243243-89-1
MW: 379.45 D
ab 73,00 €
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Wnt-C59
Wnt-C59

Artikelnummer: TGM-T2242-100mg

Description: Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity. Target: Porcupine, Wnt/beta-catenin. Smiles: Cc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(cc2)-c2cccnc2)cc1. References: Proffitt KD, et al. Cancer Res, 2013, 73(2), 502-507.
Schlagworte: C59
Anwendung: Porcupine inhibitor
CAS 1243243-89-1
MW: 379.45 D
ab 34,00 €
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