Zu "1239875-86-5" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
SGI-7079
Artikelnummer: TGM-T6982-100mg
Description: SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR inhibitor resistance. Target: FLT, c-RET, c-Met/HGFR, Src, TAM Receptor. Smiles:...
| Anwendung: | Axl inhibitor |
| CAS | 1239875-86-5 |
| MW: | 455.53 D |
ab 35,00 €
SGI-7079
Artikelnummer: Cay20111-1
SGI-7079 is an inhibitor of the receptor tyrosine kinase Axl. It inhibits proliferation of inflammatory breast cancer cells (IC50s = 0.43 and 0.15 µM for SUM149 and KPL-4 cells, respectively), decreases invasion, and halts the cell cycle in the G1 phase. SGI-7079 synergistically increases the potency of erlotinib...
| Schlagworte: | 3-[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-benzeneacetonitrile |
| Anwendung: | Axl inhibitor |
| CAS | 1239875-86-5 |
| MW: | 455.5 D |
ab 43,00 €
