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CGP 36742
Artikelnummer: TGM-T14938-2mg
Description: CGP 36742 is a selective antagonist of the GABAB receptor that can penetrate the blood-brain barrier after peripheral administration (IC50: 32 µM). It is useful in the treatment of depression. Target: GABA Receptor. Smiles: P(CCCC)(CCCN)(=O)O. References: Nowak G, et al. Antidepressant-like activity of...
| Schlagworte: | SGS-742 |
| Anwendung: | GABAB receptor antagonist |
| CAS | 123690-78-8 |
| MW: | 179.2 D |
83,00 €
CGP 36742
Artikelnummer: Cay35495-10
CGP 36742 is an antagonist of GABAB receptors (IC50 = 36 µM). It is selective for GABAB over a panel of 11 receptors, including GABAA, at 1 mM. CGP 36742 (3 mg/kg) reduces paired-pulse inhibition of the late inhibitory postsynaptic potential (IPSP) in CA1 pyramidal neurons in rats. It increases latency to step-down...
| Schlagworte: | 3-Aminopropyl-n-butylphosphinic Acid, SGS 742, P-(3-aminopropyl)-P-butyl-phosphinic acid |
| Anwendung: | GABAB receptor antagonist |
| CAS | 123690-78-8 |
| MW: | 179.2 D |
ab 204,00 €
