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Iguratimod
Artikelnummer: TGM-T5032-100mg
Description: Iguratimod (T614) is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 µM (7.7 µg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migration inhibitory factor (MIF) with an IC50 of 6.81 µM. Target: COX, Others. Smiles:...
| Schlagworte: | T614 |
| Anwendung: | Targets nuclear factor NF-kappa-B p105 subunit (NFKB1) |
| CAS | 123663-49-0 |
| MW: | 374.37 D |
ab 43,00 €
Iguratimod
Artikelnummer: Cay35529-10
Iguratimod is a disease-modifying antirheumatic drug (DMARD) and COX-2 inhibitor (IC50 = 7.7 µg/ml). It is selective for COX-2 over COX-1 (IC50 = >300 µg/ml) but also inhibits the tautomerase activity of macrophage migration inhibitory factor (MIF, IC50 = 6.81 µM). Iguratimod (1-10 µM) inhibits osteoclastogenesis...
| Schlagworte: | IGU, T-614, N-[3-(formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]-methanesulfonamide |
| Anwendung: | DMARD, COX-2 inhibitor |
| CAS | 123663-49-0 |
| MW: | 374.4 D |
ab 40,00 €
