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rac-BHFF
Artikelnummer: TGM-T4176-100mg
Description: rac-BHFF ((R,S)-BHFF) is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). It exhibits anxiolytic activity in vivo and is orally active. Target: GABA Receptor. Smiles:...
| Schlagworte: | (R,S)-BHFF |
| Anwendung: | GABA(B) receptor positive allosteric modulator |
| CAS | 123557-91-5 |
| MW: | 330.34 D |
ab 55,00 €
(R,S)-BHFF
Artikelnummer: Cay25535-10
(R,S)-BHFF is a positive allosteric modulator of GABAB receptors that increases the potency of GABA by 15.3-fold in a GTPgamma[35S] binding assay when used at a concentration of 0.3 µM. It is selective for GABAB over a panel of receptors and ion channels at 10 µM, however, it inhibits the cholecystokinin-1 (CCKA)...
| Schlagworte: | rac-BHFF, 5,7-bis(1,1-dimethylethyl)-3-hydroxy-3-(trifluoromethyl)-2(3H)-benzofuranone |
| Anwendung: | GABA(B) receptor positive allosteric modulator |
| CAS | 123557-91-5 |
| MW: | 330.3 D |
ab 85,00 €
