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APY0201
APY0201

Artikelnummer: TGM-T2061-10mg

Description: APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3, 5)P2. Target: PI3K, Interleukin. Smiles: Cc1cccc(\C=N\Nc2cc(N3CCOCC3)n3nc(cc3n2)-c2ccncc2)c1. References: Hayakawa N, et...
CAS 1232221-74-7
MW: 413.48 D
ab 71,00 €
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APY0201
APY0201

Artikelnummer: Cay9001589-5

APY0201 is an inhibitor of FYVE finger-containing phosphoinositide kinase (PIKFYVE, IC50 = 5.2 nM) that selectively inhibits interleukin-12 (IL-12) family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-alpha in stimulated human peripheral blood mononuclear cells...
Schlagworte: 2-[7-(4-morpholinyl)-2-(4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]hydrazone, 3-methyl-benzaldehyde
Anwendung: 1-phosphatidylinositol 3-phosphate 5-kinase( PIKFYVE) inhibitor
CAS 1232221-74-7
MW: 413.5 D
ab 52,00 €
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